The effects of creatine monohydrate supplementation on creatine transporter activity and creatine metabolism in resistance trained males
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چکیده
منابع مشابه
The effects of creatine monohydrate supplementation on creatine transporter activity and creatine metabolism in resistance trained males
Background Oral creatine supplementation is known to provide numerous benefits, including increases in lean muscle mass, muscular strength, and enhanced performance in various athletic capacities. The creatine transporter is a transmembrane protein that mediates the entry of creatine from the circulation into the muscle cell. Little is understood about the importance of the creatine transporter...
متن کاملMuscle creatine uptake and creatine transporter expression in response to creatine supplementation and depletion.
The total creatine pool size [Cr(total); creatine (Cr) + phosphocreatine (PCr)] is crucial for optimal energy utilization in skeletal muscle, especially at the onset of exercise and during intense contractions. The Cr(total) likely is controlled by long-term modulation of Cr uptake via the sodium-dependent Cr transporter (CrT). To test this hypothesis, adult male Sprague-Dawley rats were fed 1%...
متن کاملCreatine Monohydrate
Description Creatine is a naturally occurring amin (~1 g/day-1 [~0.04 oz.]) occurs in the glycine, arginine, and methionine. Cr daily requirement of ~2 to 3 g [~0.1 o Approximately 3 to 5 g [~0.1 to 0.2 o uncooked meat or fish. Dietary creat enters the bloodstream. Most (95 pe muscle. Sixty to seventy percent of s phosphocreatine (PCr), which is effe the anaerobic production of adenosin g [~4 o...
متن کاملCreatine Kinase Activity and Cartilage Energy Metabolism: Creatine Kinase-creatine Phosphate Circuit Activity and Macromolecule Synthesis
Earlier studies showed that there is significant creatine kinase activity in the epiphyseal growth cartilage, and there is stage-specific isoform expression. To further explore the role of this enzyme in cartilage development, we disrupted the creatine kinase creatine phosphate (CK-CP) circuit using the creatine analogue, cyclocreatine. We found that while cyclocreatine decreased creatine kinas...
متن کاملEffects of a traditionally-dosed creatine supplementation protocol and resistance training on the skeletal muscle uptake and whole-body metabolism and retention of creatine in males
Background A typical oral creatine supplementation regimen involving a 5-7 day “loading phase” of 20-25 grams/day followed by a “maintenance phase” of 5-7 grams/day is typically considered as necessary to adequately saturate skeletal muscle as a lesser dose of creatine is insufficient in doing so. This rationale also assumes that the majority, if not all, of the creatine ingested at this dosage...
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ژورنال
عنوان ژورنال: Journal of the International Society of Sports Nutrition
سال: 2015
ISSN: 1550-2783
DOI: 10.1186/1550-2783-12-s1-p43